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The majority of cell lines exhibit a steep dose response to GNE-617 when evaluated by decrease in ATP or total nucleic acid
6)7)47(64)58-25-36(60)22-38(58)46(63)52-24-32-8-10-34(11-9-32)43-29(2)53-27-68-43/h8-15
4S)-4-{(2R)-2-[(3S
PMID: 22923591
Small-molecule activation of neuronal cell fate
PF-03716556 Size:2mg solid The majority of cell linesPF 03716556 is a potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease. PF 03716556 demonstrated 3 fold greater inhibitory activity than revaprazan. PF 03716556 did not display any species differences, exhibiting highly selective profile including the canine kidney Na(+), K(+) ATPase. Kinetics experiments revealed that PF 03716556 has a competitive and reversible mode of action. Product information CAS Number: