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Chemical Name: (S)-(4-fluorophenyl)(3-(3-(4-fluorophenyl)-1
347174-05-4
Dovitinib significantly reduces the basal phosphorylation levels of FGFR-1
L002 was shown to occupy Ac-CoA binding pocket of p300
InChi: InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-14-6-13(18)12(17)5-10(14)15(11)19/h1-7
Dabrafenib Mesylate - CAS# 1195768-06-9 size:10mg solid Chemical Name: (S)-(4-fluorophenyl)(3-(3-(4-fluorophenyl)-1Dabrafenib Mesylate, CAS No. 1195768 06 9, also known as GSK2118436 , is an orally bioavailable inhibitor of B raf (BRAF) protein with potential antineoplastic activity. Dabrafenib selectively binds to and inhibits the activity of B raf, which may inhibit the proliferation of tumor cells which contain a mutated BRAF gene. B raf belongs to the the raf mil family of serine threonine protein kinases and plays a role in regulating the MAP kinase ERKs
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