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Formula: C39H52N4O8
an effective prodrug of Timolol
Smiles: C[C@H]1CC=CC(=O)[C@@H](O)[C@@H](O)C[C@H]2O[C@@H]2C2=CC(=CC(O)=C2C(=O)O1)OC |c:3|
In also increases release for prostaglandin D2 metabolites and inhibits production of thymic stromal lymphopoietin in dermatitis models
5-dimethyl-4
PROTAC BRD2/BRD4 degrader-1 in C Formula: C39H52N4O8PROTAC BRD2 BRD4 degrader 1 (compound 15) is a potent and selective BET protein BRD4 and BRD2 degrader. PROTAC BRD2 BRD4 degrader 1 rapidly induces reversible, long lasting, and unexpectedly selective removal of BRD4 and BRD2 over BRD3. It effectively inhibits solid tumors with low cytotoxic effect. PROTAC BRD2 BRD4 degrader 1 is composed of the BET inhibitor, a linker, and the ligand thalidomide for cereblon (CRBN) cullin 4A. Product information
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