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1-4H3/b11-5-/t16-/m0/s1
Oral administration of CX-4945 at 25 mg/kg or 75 mg/kg twice daily displays potent antitumor activity in the BT-474 model
It has selectivity > 1000-fold over 13 other HMTs and selected representatives of kinases
rats receiving Mibefradil or NSC 64013 show significant lower CaV3
but is significantly less potent against the rat liver isoform (IC50=11 μM)
VH 032 amide-alkylC6-acid - CAS# 2172819-75-7 791343 dihydrochloride 1-4H3/b11-5-/t16-/m0/s1VH 032 amide alkylC6 acid, CAS No. 2172819 75 7, is a VHL ligand with alkyl linker and terminal acid for onward chemistry. Product information CAS Number: 2172819 75 7 Molecular Weight: 586. 74 Formula: C30H42N4O6S Synonym: VH 032 amide alkylC6 acid VH 032 amide alkylC6 VH032 amide alkylC6 acid VH032amide alkylC6 acid VH 032amide alkylC6 Chemical Name: 8 (((S) 1 ((2S,4R) 4 hydroxy 2 ((4 (4 methylthiazol 5 yl)benzyl)carbamoyl)pyrrolidin 1 yl) 3,3