JNJ-64619178 Size:Contact [email protected] for quotation InChi: InChI=1S/C30H26O13/c31-14-7-19(35)16-11-25(28(41-23(16)9-14)12-1-3-17(33)20(36)5-12)43-30(13-2-4-18(34)21(37)6-13)29(40)27(39)26-22(38)8-15(32)10-24(26)42-30/h1-10

InChi: InChI=1S/C30H26O13/c31-14-7-19(35)16-11-25(28(41-23(16)9-14)12-1-3-17(33)20(36)5-12)43-30(13-2-4-18(34)21(37)6-13)29(40)27(39)26-22(38)8-15(32)10-24(26)42-30/h1-10

Galmarini CM

Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells

male albino Sprague-Dawley rats) treatment significantly decreases the number of spontaneously active ventral tegmental area (VTA) dopaminergic neurons

Smiles: COCCN(C)C1C=CC(=CC=1)NC(=O)C1N=C(OC=1C(F)(F)F)C1C=CC=CC=1

JNJ-64619178 Size:Contact [email protected] for quotation InChi: InChI=1S/C30H26O13/c31-14-7-19(35)16-11-25(28(41-23(16)9-14)12-1-3-17(33)20(36)5-12)43-30(13-2-4-18(34)21(37)6-13)29(40)27(39)26-22(38)8-15(32)10-24(26)42-30/h1-10JNJ 64619178 is a selective, orally active and pseudo irreversible protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 0. 14 nM. JNJ 64619178 has potent activity In lung cancer. Product information CAS Number: 2086772 26 9 Molecular Weight: 483. 36 Formula: C22H23BrN6O2 Chemical Name: (1S,2R,3S,5R) 3 [2 (2 amino 3 bromoquinolin 7 yl)ethyl] 5 {4 amino 7H pyrrolo[2,3 d]pyrimidin 7 yl}cyclopentane 1,2 diol Smiles: