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Hildebrand JM
KB-R7943 inhibits high glucose-induced endothelial ICAM-1 expression and monocyte-endothelial adhesion
activin receptor-like kinase (ALK5)
InChi: InChI=1S/C22H24BrFN4O2
]pentadeca-1(15)
PHA-767491 Hydrochloride - CAS# 942425-68-5 noxerine Hildebrand JMPHA 767491, also known as CAY10572, is a potent, ATP competitive dual cdc7 cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication. PHA 767491 Suppresses Hepatocarcinoma Synergistically with 5 Fluorouracil. PHA 767491 in combination with 5 FU exhibited much stronger cytotoxicity and induced significant apoptosis manifested by remarkably increased caspase 3 activation and poly(ADP Ribose) polymerase
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