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InChiKey: XOGQXKBFJZURRD-HQROKSDRSA-N
reversible inhibitor of recombinant Aurora A kinase with an IC50 of 4 nM
Smiles: CCS(O)(=O)=O
Activation of the PI3K signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents
23)/t10-/m0/s1
L-745870 trihydrochloride Size:Contact [email protected] for quotation InChiKey: XOGQXKBFJZURRD-HQROKSDRSA-NL 745870 trihydrochloride is a potent, selective, brain penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0. 43 nM. L 745870 trihydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5 HT2 receptors, sigma sites and adrenoceptors. Product information CAS Number: 866021 03 6 Molecular Weight: 436. 21 Formula: C18H22Cl4N4 Chemical Name: 1 (4 chlorophenyl) 4
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