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Azelastine
781661-94-7
is an apoptosis inducer
it strongly induced the filamentation in B
Smiles: COC1C=C2C(=CNC2=CC=1)C1CCNCC=1
D-α-Hydroxyglutaric acid odesine AzelastineD Hydroxyglutaric acid ((R) 2 Hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D 2 hydroxyglutaric aciduria. D Hydroxyglutaric acid is a weak competitive antagonist of ketoglutarate ( KG) and inhibits multiple KG dependent dioxygenases with a Ki of 10. 87 mM. D Hydroxyglutaric acid increases reactive oxygen species (ROS) production. D Hydroxyglutaric acid binds and inhibits ATP synthase and inhibits mTOR signaling.