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InChiKey: CMSMOCZEIVJLDB-UHFFFAOYSA-N
OTS964 hydrochloride (intravenously
preventing invasion in glioma cells destabilizing amyloid-β aggregates and preventing fibril assembly
InChi: InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32
4-triazol-1-yl)-1H-pyrrolo[2
SU14813 maleate - CAS# 849643-15-8 Size:Solid 10 mg InChiKey: CMSMOCZEIVJLDB-UHFFFAOYSA-NSU14813 is an oral, multitargeted tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptors (VEGFR), platelet derived growth factor receptors (PDGFR), KIT, and fms like tyrosine kinase 3 (FLT 3) (1). SU14813 was developed as a next generation TKI agent following sunitinib (SU11248) designed to demonstrate optimized pharmacokinetic (PK) and tolerability profiles. SU14813 demonstrated broad and potent antitumor activity
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