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Formula: C30H24F3N7O3
MAPK and Akt pathways
Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs
Smiles: CCCNC(=O)NS(=O)(=O)C1=CC=C(Cl)C=C1
Smiles: COC1=CC2=NC=NC(NC3=CC(Cl)=C(F)C=C3)=C2C=C1O
TAK-683 acetate 27620 Formula: C30H24F3N7O3TAK 683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK 683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0. 96 nM and 1. 6 nM for human and rat, respectively. TAK 683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone dependent prostate
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