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Epub 2010 Jan 29
Treatment of growing AML cells with RO-3306 induced G2/M-phase cell cycle arrest and apoptosis in a dose- and time-dependent manner
Formula: C18H15ClN4O2
29)30)18-10-6-4-7-11-18)25-19-12-14-20(15-13-19)26-16-8-5-9-17-26/h4
and P2X2-X3
O-Methylviridicatin R-VIVIT TFA Epub 2010 Jan 29IC50: 2. 5 M: inhibits virus production in OM 10. 1 cells (HL 60 promyelocytes infected with HIV 1) treated with TNF . 5 M: blocks activation of the HIV long terminal repeat by TNF in HeLa cells O Methylviridicatin, a natural derivative of the alkaloid mycotoxin viridicatin, is produced by several species in the genus, Penicillium. It is demonstrated that O Methylviridicatin, as an inhibitor, blocks the tumor necrosis factor alpha (TNF) induced
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