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Eprodisate Sodium - CAS# 36589-58-9 Catalog No.:M11419-10 Impact of a baseline polymorphism

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Description

Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus nonstructural protein 5A replication complex inhibitor

CAS Number: 286930-03-8

6R)-2-{[(2R

InChiKey: KOQIAZNBAWFSQM-UHFFFAOYSA-N

Sandrock JE

Eprodisate Sodium - CAS# 36589-58-9 Catalog No.:M11419-10 Impact of a baseline polymorphismEprodisate, also known as 3 PDS; NC 503; 3PDS, is an orally available disodium salt form of eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis. Upon administration, eprodisate competitively binds to the glycosaminoglycan binding sites on serum amyloid A (SAA), which inhibits the formation of the glycosaminoglycan amyloid fibril aggregate. This prevents the formation

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