E7090 succinate in acid ammonium LumiLuc-8pyDTZ pair is compared with

LumiLuc-8pyDTZ pair is compared with several benchmark reporters in a tumor xenograft mouse model

InChi: InChI=1S/C21H23Cl2N3O/c1-3-11-25(12-4-2)20(27)13-18-21(15-5-7-16(22)8-6-15)24-19-10-9-17(23)14-26(18)19/h5-10

W-7 is distributed mainly in the cytoplasm

DHODH-IN-8 has antimalarial activity

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E7090 succinate in acid ammonium LumiLuc-8pyDTZ pair is compared withE7090 succinate is an orally available, selective and potent inhibitor of FGFR1, FGFR2 and FGFR3 tyrosine kinase activities, with IC50 values of 0. 71 nM, 0. 50 nM, 1. 2 nM, and 120 nM for FGFR1 2 3 4, respectively. Product information CAS Number: 1879965 80 6 Molecular Weight: 705. 75 Formula: C36H43N5O10 Chemical Name: 5 [(2 {4 [1 (2 hydroxyethyl)piperidin 4 yl]benzamido}pyridin 4 yl)oxy] 6 (2 methoxyethoxy) N methyl 1H indole 1 carboxamide;