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van Bochove GG
Adão-Novaes J
Smiles: C(C1C=CC=CC=1)N1C(=NN=C1SC1=NC=NC2=C1SC1=NC=CC=C21)C1C=CN=CC=1
InChi: InChI=1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8H
Pyrogallol inhibits Calu-6 and A549 lung cancer cell growth via apoptosis and depletion of glutathione (GSH)
tert-Butyl 11-aminoundecanoate y cyclophosphamide van Bochove GGtert Butyl 11 aminoundecanoate (compound 6b) is a PROTAC linker, which refers to the PEG composition. tert Butyl 11 aminoundecanoate can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin proteasome system to selectively degrade target proteins. Product information
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