KN-92 - CAS# 176708-42-2 or KRAS Chemical Name: 4-{[4-(4-cyclopropylpiperazine-1-carbonyl)phenyl]methyl}morpholine

Chemical Name: 4-{[4-(4-cyclopropylpiperazine-1-carbonyl)phenyl]methyl}morpholine

InChi: InChI=1S/C30H31FN2O/c31-25-12-14-26(15-13-25)33-21-23(27-9-2-4-11-29(27)33)7-5-6-18-32-19-16-30(17-20-32)28-10-3-1-8-24(28)22-34-30/h1-4

and colon tumor xenografts by oral dosing

35)20-10-5-7-17(12-20)27(33)31(2)3)14-22-24(16)29-15-23(26(28)32)25(22)30-18-8-6-9-19(13-18)36-4/h5-15H

(S)-Crizotinib is a useful chemical probe to further validate MTH1 as a promising novel class of anticancer target

KN-92 - CAS# 176708-42-2 or KRAS Chemical Name: 4-{[4-(4-cyclopropylpiperazine-1-carbonyl)phenyl]methyl}morpholineKN 92 is an inactive analog of the CaM kinase II inhibitor KN 93. Product information CAS Number: 176708 42 2 Molecular Weight: 456. 98 Formula: C24H25ClN2O3S Synonym: KN 92 KN92 Chemical Name: N [2 ({[(2E) 3 (4 chlorophenyl)prop 2 en 1 yl](methyl)amino}methyl)phenyl] 4 methoxybenzene 1 sulfonamide Smiles: COC1C=CC(=CC=1)S(=O)(=O)NC1=CC=CC=C1CN(C)C C=C C1C=CC(Cl)=CC=1 InChiKey: RUAOVVIUGUOYHA AATRIKPKSA N InChi: InChI=1S C24H25ClN2O3S c1 27(17 5 6 19