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GRP-60367 - CAS# 1309241-34-6 size:10mg solid Simpson PB

SKU: 25375523558

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Description

Simpson PB

InChi: InChI=1S/C21H18F3NO3S2/c1-12-9-16(7-8-17(12)28-10-19(26)27)29-11-18-13(2)25-20(30-18)14-3-5-15(6-4-14)21(22

Formula: C51H79NO13

C2H2O4/c1-2-16-8-4-6-13-21(16)24-15-18(23)14-22-20-12-7-10-17-9-3-5-11-19(17)20

7-dimethoxy-4-quinazolinyl)amino]phenol

GRP-60367 - CAS# 1309241-34-6 size:10mg solid Simpson PBGRP 60367, CAS No. 1309241 34 6, is a potent and selective rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains. GRP 60367 inhibits entry of a subset of RABV strains. Resistance profiling of the chemotype revealed hot spots in conserved hydrophobic positions of the RABV G protein fusion loop that were confirmed in transient cell to cell fusion assays. Transfer of RABV G genes with signature resistance mutations into a

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