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Smiles: O=C1C(=COC21OC(=O)C1=CC=CC=C21)C1C=CC=CC=1
2018 Feb 19
012 μg/mL
33(10):4411-20
In the SJSA-1 osteosarcoma
P-1075 03580 Smiles: O=C1C(=COC21OC(=O)C1=CC=CC=C21)C1C=CC=CC=1P 1075 is a potent activator of sulfonylurea receptor 2 associated ATP sensitive potassium channels (SUR2 KIR6), with an EC50 value of 45 nM for SUR2B KIR6 channel activation. P 1075 also P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts. Product information CAS Number: 60559 98 0 Molecular Weight: 231. 30 Formula: C12H17N5 Chemical Name: (Z) N' cyano N (2 methylbutan 2 yl)
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