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1(4):247-56
Targeting the Transforming Growth Factor-β Signaling in Cancer Therapy
PubMed PMID: 25241015
Erichsen HK
DU-145 prostate cancer
BS-181 HCl - CAS# 1397219-81-6 Catalog No.:M6415-2 1(4):247-56BS 181 HCl, CAS No. 1397219 81 6, is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more than 40 fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9. Product information CAS Number: 1397219 81 6 Molecular Weight: 416. 99 Formula: C22H33ClN6 Chemical Name: BS 181 HCl Smiles: Cl. CC(C)C1C=NN2C(=CC(NCCCCCCN)=NC2=1)NCC1C=CC=CC=1 InChiKey: NVIJWMOQODWNFN UHFFFAOYSA N InChi: InChI=1S C22H32N6. ClH c1 17(2)19 16 26 28 21(25 15 18 10 6 5 7 11
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