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Pactimibe (CS-505 free base) induces moderate ACAT inhibition in monocyte-derived macrophages
CAS Number: 2313525-20-9
CAS Number: 2357113-68-7
and TBA levels at 14 and 21 d time points when compared with that of the RIF and INH group
once daily for 30 days) has a not significant influence in the ovaries from mice at the dose of 3 mg/kg
8-CPT-2Me-cAMP, sodium salt 283psilon-(gamma-glutamyl)-lysine Pactimibe (CS-505 free base) induces8 CPT 2Me cAMP, sodium salt is a selective agonist of EPAC . Cyclic AMP guanine nucleotide exchange factors (EPACs) are intracellular sensors for cAMP and function as nucleotide exchange factors for the Ras GTPase homologues Rap1 and Rap2 . 8 CPT 2Me cAMP, sodium salt is a selective EPAC agonist. 8 CPT 2Me cAMP increased Rap1 activation by EPAC1. Meantime, light chain 2 (LC2) of the microtubule associated protein MAP1A increased this response. In LC2
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