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inhibiting cell growth by 50–100% at 10 μM in 40 of 48 cell lines tested
For Sight: The Future of Eye and Vision Research--part 2
InChi: InChI=1S/C33H43N5O4/c1-22(2)35-33(40)36-27-14-15-30-28(17-27)32(39)37(5)20-31(41-6)23(3)18-38(24(4)21-42-30)19-25-10-12-26(13-11-25)29-9-7-8-16-34-29/h7-17
It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions
CYP2C9 and CYP2D6
DVD-445 nib mesylate inhibiting cell growth by 50–100%DVD 445 (Compound 7) is a potent peptidomimetic covalent thioredoxin reductase 1 (TrxR1) inhibitor with an IC50 of 0. 60 M for rat TrxR1. DVD 445 has good anticancer application. Product information CAS Number: 2375846 41 4 Molecular Weight: 458. 50 Formula: C25H28F2N2O4 Chemical Name: 2 {[(tert butylcarbamoyl)(4 fluorophenyl)methyl](methyl)amino}ethyl (2E) 4 (4 fluorophenyl) 4 oxobut 2 enoate Smiles: CN(CCOC(=O) C=C