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GSK1904529A blocks receptor autophosphorylation and downstream signaling
especially in irritable bowel syndrome
inhibits cell growth and apoptosis in many more cell lines and at lower concentrations as compared to the PI3K-selective inhibitors XL147 and PIK90
CC(C)(C)[C@@H]1NC(=O)O[C@@H]2C[C@H]2CCCCCC2=NC3=CC=C(C=C3N=C2O[C@@H]2C[C@@H](C(=O)N[C@@]3(C[C@H]3C=C)C(=O)NS(=O)(=O)C3CC3)N(C2)C1=O)OC
Chemical Name: 2-([1
MK-3207 - CAS# 957118-49-9 Catalog No.:M10581-10 GSK1904529A blocks receptor autophosphorylation andMK 3207 is a potent and orally active calcitonin gene related peptide receptor antagonist. Calcitonin gene related peptide (CGRP) receptor antagonists are effective acute migraine treatments. (Ki = 0. 024 nM). Product information CAS Number: 957118 49 9 Molecular Weight: 557. 59 Formula: C31H29F2N5O3 Synonym: MK3207 MK 3207 Chemical Name: 2 [(8R) 8 (3,5 difluorophenyl) 10 oxo 6,9 diazaspiro[4. 5]decan 9 yl] N [(2R) 2' oxo 1,1',2',3
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