GRL-0496 - CAS# 1087243-14-8 D9567 toremifene citrate is FDA-approved for

toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer

it modestly inhibits two cytochrome P450 family members (CYP-2B6 IC50

GDP366 induces polyploidy in multiple types of cancer cell lines

BSc3094 (0

Smiles: CC[C@@H](C)[C@@H]1OC2(C[C@@H]3C[C@H](CC=C(C)[C@H](O[C@H]4C[C@H](OC)[C@H](O[C@H]5C[C@H](OC)[C@H](NC(C)=O)[C@H](C)O5)[C@H](C)O4)[C@H](C)C=CC=C4CO[C@H]5[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@@]45O)O2)C=C[C@H]1C |c:12

GRL-0496 - CAS# 1087243-14-8 D9567 toremifene citrate is FDA-approved forGRL 0496 is a potent chloropyridyl ester derived SARS CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL 0496 shows SARS CoV antiviral activity, with an EC50 of 6. 9 M. Product information CAS Number: 1087243 14 8 Molecular Weight: 272. 69 Formula: C14H9ClN2O2 Chemical Name: 5 chloropyridin 3 yl 1H indole 4 carboxylate Smiles: O=C(OC1=CN=CC(Cl)=C1)C1C=CC=C2NC=CC=12 InChiKey: BOSZJNSICHFHMA UHFFFAOYSA N