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PubMed PMID: 23650921
Pasternak A
Objective responses were not observed for the solid tumor or ALL xenografts
1H2/b23-12-
compared with other receptor tyrosine kinases
AVL-292 (benzenesulfonate) X-222 PubMed PMID: 23650921Spebrutinib, also known as AVL 292 or CC 292, is an orally bioavailable, selective inhibitor of Brutons agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, AVL 292 targets and covalently binds to BTK, thereby preventing its activity. Product information CAS Number: 1360053 81 1 Molecular Weight: 581. 62 Formula: C28H28FN5O6S Synonym: Spebrutinib besylate CC 292 besylate Chemical Name: N {3 [(5 fluoro
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