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PF-04979064 exhibited excellent in vitro potency
and nucleic acid and lipid biosynthesis
4 μM and 4
HPOB was dosed to mice bearing CWR22 human prostate cancer xenografts at 300 mg/kg once per day by IP injection
Lairson LL
Danshensu sodium salt Catalog No.:M7627-2 PF-04979064 exhibited excellent in vitroDanshensu (sodium salt) is odium salt of danshensu from the widely used Chinese herb Danshen. It can inhibited phenylephrine and CaCl2 induced vasoconstriction in Ca2+ free medium. In vitro: Sodium danshensu showed a biphasic effects on vessel tension. While low dosage of sodium danshensu produced small contraction possibly through transient enhancement of Ca2+ influx, high dosage produced significant vasodilation mainly through promoting the opening
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