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Selective for TRPV2 over TRPV1
Therefore the Amuvatinib dose is reduced to 10 mg/kg or 20 mg/kg for the combination treatment
InChi: InChI=1S/C33H34N4O3/c1-20-17-37(18-21(2)40-20)19-23-6-4-22(5-7-23)8-12-29-26-11-9-24(14-31(26)36-35-29)28-16-33(28)27-15-25(39-3)10-13-30(27)34-32(33)38/h4-15
Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCCCCCCCl)C(C)(C)C)=CC=1
2ClH/c15-5-7-23-14(24-8-6-16)9-1-3-10(4-2-9)19-13-21-11(17)20-12(18)22-13
SNX-482 Catalog No.:M30731-C Selective for TRPV2 over TRPV1SNX 482, a peptidyl toxin of the spider Hysterocrates gigas, is a potent, high affinity, selective and voltage dependent R type CaV2. 3 channel blocker with an IC50 of 30 nM. SNX 482 has antinociceptive effect. Product information CAS Number: 203460 30 4 Molecular Weight: 4495. 00 Formula: C192H274N52O60S7 Chemical Name: 2 {2 [2 (2 {2 [2 (2 {2 [(24 {2 [2 (6 amino 2 {2 [2 (2 aminoacetamido) 3 methylbutanamido] 3
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