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H4R antagonist 1 35 mesylate Anemarsaponin B inhibits the nuclear

SKU: 1893255978

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Description

Anemarsaponin B inhibits the nuclear translocation of the p65 subunit of NF-κB by blocking the phosphorylation of IκBα

5-bis[(thiophen-2-yl)methylidene]cyclopentan-1-one

Cloning and functional expression of GABA(B) receptors from Drosophila

InChiKey: FMLUAKSJMUPACD-WQLSENKSSA-N

Smiles: C[C@@H]1O[C@@H](O[C@H]2[C@H](OC(=O)/C=C/C3=CC(O)=C(O)C=C3)[C@@H](CO)O[C@@H](OCCC3C=C(O)C(O)=CC=3)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O

H4R antagonist 1 35 mesylate Anemarsaponin B inhibits the nuclearH4R antagonist 1 is a potent and highly selective histamine H4 receptor (H4R) antagonist with an IC50 of 27 nM. H4R antagonist 1 does not show any noticeable binding affinity to other subtypes of histamine receptors, H1R, H2R, and H3R. Product information CAS Number: 1429375 54 1 Molecular Weight: 335. 16 Formula: C11H11BrN8 Chemical Name: 1 {12 bromo 2,3,4,5,8,10 hexaazatricyclo[7. 4. 0. 0,]trideca 1(9),3,5,7,10,12 hexaen 7 yl} N methylazetidin 3

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