Zoniporide hydrochloride hydrate 8810 with an EC50 and IC50

with an EC50 and IC50 of 10 nM and 260 nM for human PPARα and ∼410-fold and more than 57-fold selectivity vs human PPARγ of 4100 nM and >15000 nM in PPAR-GAL4 transactivation assays

928672-86-0

Formula: C11H8O4

which prolongs action potential and refractory period (physiology) of myocardial cells

14-9-/t13-

Zoniporide hydrochloride hydrate 8810 with an EC50 and IC50Zoniporide (CP 597396) hydrochloride hydrate is a potent and selective inhibitor of sodium hydrogen exchanger type 1 (NHE 1). Zoniporide hydrochloride hydrate inhibits human NHE 1 (IC50=14 nM), and has >150 fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE 1 dependent swelling of human platelets (IC50=59 nM). Product information CAS Number: 863406 85 3 Molecular Weight: 374. 82 Formula: