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1-4H3/t20-/m1/s1
IC50 of BMN 673 ranges between 90 nM and 1
is a potent and selective cytokine release inhibitor and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases
casein kinase-1
Cetirizine (free base) is a potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis
NSC-87877 pyridine-2-carboxylate 1-4H3/t20-/m1/s1NSC 87877 is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH PTP2 and SH PTP1), with IC50 values of 0. 318 M, 0. 355 M shp2 and shp1, respectively. NSC 87877 also inhibits dual specificity phosphatase 26 (DUSP26). Product information CAS Number: 56990 57 9 Molecular Weight: 459. 45 Formula: C19H13N3O7S2 Chemical Name: 8 oxo 7 [2 (6 sulfonaphthalen 2 yl)hydrazin 1 ylidene] 7,8 dihydroquinoline 5 sulfonic acid Smiles: