Cilofexor mol hemisulfate and TNF-α is introduced as

and TNF-α is introduced as a positive control for NF-κB activation

is a potent monoamine transporter inhibitor

Epub 2018 Nov 13

SB-267268 (60 mg/kg

1-100000 nM

Cilofexor mol hemisulfate and TNF-α is introduced asCilofexor (GS 9674) is a potent, selective and orally active nonsteroidal FXR agonist with an EC50 of 43 nM. Cilofexor has anti inflammatory and antifibrotic effects. Cilofexor has the potential for primary sclerosing cholangitis (PSC) and nonalcoholic steatohepatitis (NASH) research. Product information CAS Number: 1418274 28 8 Molecular Weight: 586. 85 Formula: C28H22Cl3N3O5 Chemical Name: 2 [3 (2 chloro 4 {[5 cyclopropyl 3 (2,6 dichlorophenyl) 1,2