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UF010 inhibits cancer cell proliferation via class I HDAC inhibition
InChi: InChI=1S/C18H18N2S/c1-3-4-16-11-15(9-10-19-16)18-20-17(12-21-18)14-7-5-13(2)6-8-14/h5-12H
The use of BMS-201038 alone or in combination with other lipid-lowering modalities reduces plasma concentrations of low density lipoprotein cholesterol (LDL-C) by a mean of more than 50%
which are inhibited by Aβ25-35 treatment
17(5):877-86
CK-636 - CAS# 442632-72-6 434 UF010 inhibits cancer cell proliferationCK 636, CAS No. 442632 72 6, is a Arp2 3 complex inhibitor. CK 636 binds between Arp2 and Arp3, where it appears to block movement of Arp2 and Arp3 into their active conformation. CK 636 inserts into the hydrophobic core of Arp3 and alters its conformation. Polymerization of actin filaments directed by the actin related protein (Arp)2 3 complex supports many types of cellular movements. CK 636 may be a powerful tool compound for studying the Arp2 3
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