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17-AAG Hydrochloride zithromycin Selvaraju K

SKU: 17542303055

4.7
USD100.00 USD129.00

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Ships within 48 hours · Estimated delivery Aug 4 - Aug 9

Description

Selvaraju K

1009820-21-6

Formula: C11H15BrN2O

Patsharaporn T Sarasombath

Harrington B

17-AAG Hydrochloride zithromycin Selvaraju K17 AAG hydrochloride is a potent HSP90 inhibitor with IC50 value of 5 nM, which is a 100 fold higher binding affinity for HSP90 derived from tumour cells than that from normal cells. It is less toxic by binding to Hsp90 and altering its function. It causes the degradation of HER2, HER3, Akt, and both mutant and wild type androgen receptor (AR), leading to the RB dependent G1 growth arrest of prostate cancer cells. It has the ability to induce

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