without growth inhibition of BaF3 cells transformed by other oncogenic tyrosine kinases
It is a weak inhibitor of PKA with an IC50 of 30 μM
PubMed PMID: 23774824
25)18-11-14(20)10-15(21)19(18)23/h2-11
H-1152 is a more specific
(S, R, S)-AHPC-Me ortmannin without growth inhibition of BaF3(S, R, S) AHPC Me is the (S, R, S) AHPC based VHL ligand used in the recruitment of the von Hippel Lindau (VHL) protein. (S, R, S) AHPC Me can be used to synthesize ARV 771, a BET PROTAC degrader. Product information CAS Number: 1948273 02 6 Molecular Weight: 444. 59 Formula: C23H32N4O3S Synonym: VHL ligand 2 E3 ligase Ligand 1A Chemical Name: (2S, 4R) 1 [(2S) 2 amino 3, 3 dimethylbutanoyl] 4 hydroxy N [(1S) 1 [4 (4 methyl 1, 3 thiazol 5