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BDP5290 reduces MLC phosphorylation (pMLC) to undetectable levels
Tenovin-1 treatment does not alter p53 mRNA levels
384(1):166-9
Visconte V
Formula: C28H33N7O2
Ganetespib Size:Solid 2 mg BDP5290 reduces MLC phosphorylation (pMLC)Ganetespib, also known as STA 9090, is a synthetic small molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor STA 9090 binds to and inhibits Hsp90, resulting in the proteasomal degradation of oncogenic client proteins, the inhibition of cell proliferation and the elevation of heat shock protein 72 (Hsp72); it may inhibit the activity of multiple kinases, such as c Kit, EGFR, and Bcr Abl, which as
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