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It inhibis formation of gastric mucosal lesions
and inhibits wet-dog shakes (WDS)-like cold hypersensitivity in mice by 63% at 30 mg/kg
017 μM for BRD2
Clemizole blocks TRPC5 currents irrespectively of the mode of activation
1) Background Potassium Channel
SB-408124 Hydrochloride - CAS# 1431697-90-3 Catalog No.:M9976-2 It inhibis formation of gastricSB 408124 is a elective non peptide orexin OX1 receptor antagonist (Kb values are 21. 7 and 1405 nM for human OX1 and OX2 receptors respectively). A critical role for the orexin 1 receptor (OX1R) in complex emotional behavior is emerging, such as overactivation of the OX1R pathway being associated with panic or anxiety states. Product information CAS Number: 1431697 90 3 Molecular Weight: 392. 83 Formula: C19H19ClF2N4O Synonym: SB 408124 Hydrochloride
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