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AK-7 treatment resulted in improved motor function
SC-514 dose-dependently inhibits RANKL-induced osteoclastogenesis and induced apoptosis and caspase 3 activation in RAW264
LB-100 enhanced the effects of sorafenib in HCC cells only during hypoxic environments
176-fold more selective for class I HDACs
43-29(45)22(3)4)31(47)41-27(10-9-21-40-33(38)39)30(46)44-35(19-7-8-20-35)32(48)42-28(23-11-15-25(36)16-12-23)24-13-17-26(37)18-14-24/h11-18
VER-49009 Size:Solid 10 mg AK-7 treatment resulted in improvedVER 49009 is a potent HSP90 inhibitor. VER 49009 inhibits Hsp90 with an IC50 value of 47 nM. VER 49009 produces a cellular antiproliferative GI50 value of 685 nM when tested against a human cancer cell line panel. Consistent with inhibition of Hsp90, VER 49009 induces the expression of Hsp27 and Hsp72 while reducing the client proteins C RAF, B RAF, survivin, and PRMT5, causing cell cycle arrest and apoptosis. Product information CAS Number: 558640 51
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