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11aS)-1-acetyl-9b-hydrogenio-7-{[(2R
InChiKey: XSMABFRQESMONQ-SFHVURJKSA-N
pre- 1 hour) significantly down-regulates the mRNA levels of TNF-α and IL-6 in LPS-induced RAW 264
TCO-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs
splenomegaly
Caspase-3/7 Inhibitor I Catalog No.:M23015-C 11aS)-1-acetyl-9b-hydrogenio-7-{[(2RCaspase 3 7 inbibitor I is a potent, reversible, isatin sulfonamide based inhibitor of caspase 3 (KI(app) = 60 nM) and caspase 7 (KI(app) = 170 nM). Is a weaker inhibitor of caspase 9 (Ki(app) = 3. 1 mM). It Has only a trivial effect (Ki(app) >25 mM) on the activities of caspase 1, caspase 2, caspase 4, caspase 6, and caspase 8. It has been shown to inhibit apoptosis in camptothecin treated Jurkat cells (IC50 ~50 M). Also it has been reported to
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