Calpeptin - CAS# 117591-20-5 odeoxycholate Discovery of non-covalent inhibitors of

Discovery of non-covalent inhibitors of the SARS main proteinase 3CLpro

Formula: C23H21Cl2FN4O3

6R)-2-[3-Hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3

PIK-III is a selective inhibitor of VPS34 that binds a unique hydrophobic pocket not present in related kinases such as PI3Kα

and an antiproliferative effect on SK-MEL-2 cells (IC50 = 900 nM)

Calpeptin - CAS# 117591-20-5 odeoxycholate Discovery of non-covalent inhibitors ofCalpeptin is a potent, cell penetrating calpain inhibitor, with an ID50 of 40 nM for Calpain I in human platelets[1]. Calpeptin is also an inhibitor of cathepsin K. Product information CAS Number: 117591 20 5 Molecular Weight: 362. 46 Formula: C20H30N2O4 Chemical Name: benzyl N [(1S) 3 methyl 1 {[(2S) 1 oxohexan 2 yl]carbamoyl}butyl]carbamate Smiles: CC(C)C[C@H](NC(=O)OCC1C=CC=CC=1)C(=O)N[C@@H](CCCC)C=O InChiKey: PGGUOGKHUUUWAF ROUUACIJSA N InChi: