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Crenolanib
Biliary excretion clearance of Fexofenadine (17 ml/min/kg) accounts for almost 60% of the total body clearance (30 ml/min/kg) in mice
Asian J Androl
Epub 2015 Sep 2
InChi: InChI=1S/C29H36O15/c1-11-22(32)24(34)26(36)28(41-11)40-10-20-23(33)25(35)27(37)29(44-20)42-13-7-14(30)21-15(31)9-17(43-19(21)8-13)12-4-5-16(38-2)18(6-12)39-3/h4-8
Melflufen sant CrenolanibMelflufen (Melphalan flufenamide), a dipeptide prodrug of Melphalan, is an alkylating agent. Melflufen shows antitumor activity against multiple myeloma (MM) cells and inhibits angiogenesis. Melflufen induces irreversible DNA damage and cytotoxicity in MM cells. Product information CAS Number: 380449 51 4 Molecular Weight: 498. 42 Formula: C24H30Cl2FN3O3 Chemical Name: ethyl (2S) 2 [(2S) 2 amino 3 {4 [bis(2 chloroethyl)amino]phenyl}propanamido] 3 (4