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InChiKey: ZULJGOSFKWFVRX-UHFFFAOYSA-N
NGB 2904 can be used for the research of cocaine addiction
10 570 PMID: 25415586
5-dihydroxy-6-methyloxan-3-yl]oxy}-3
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Tivozanib (hydrate) Size:Contact [email protected] for quotation InChiKey: ZULJGOSFKWFVRX-UHFFFAOYSA-NTivozanib, also known as AV 951 and KRN 951, is an orally active, ATP competitive, small molecule, quinoline urea derivative. Tivozanib is a pan VEGFR tyrosine kinase inhibitor. In vitro: Tivozanib markedly inhibited the ligand induced phosphorylation of VEGFR1\2 and 3 with the IC50 value of 30 nM\6. 5 nM and 15 nM, respectively. Tivozanib also exihibited inhibitory effects on PDGFR and c Ki with the IC50 value of 1. 72 and 1. 63 nmol L, respectively.