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10(15):5187-201
Pagratis N
blocked EGF-stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM)
Smiles: OC1(CN(C1)C(=O)C1=CC=C(F)C(F)=C1NC1=CC=C(I)C=C1F)C1CCCCN1
Trypanosoma brucei brucei (IC50=77 nM)
Propargyl-PEG1-acid Catalog No.:M14430-2 10(15):5187-201Propargyl PEG1 acid is a PEG based PROTAC linker can be used in the synthesis of BTK CRBN PROTACs Ibrutinib(HY 10997) based PROTAC 4 and PROTAC 5. PROTAC 5 causes the degradation of BTK and induces the degradation of CSK, LYN, and LAT2 at 10 M. Product information CAS Number: 55683 37 9 Molecular Weight: 128. 13 Formula: C6H8O3 Chemical Name: 3 (prop 2 yn 1 yloxy)propanoic acid Smiles: C#CCOCCC(O)=O InChiKey: GMFDYXLFHSFUHE UHFFFAOYSA N InChi: