WYE-687 IR-124 orally bioavailable inhibitor of class

orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer

binding to p53dN

Ro 31-8220 (1 μM) is neuroprotective against paraoxon-induced neuronal cell death in cerebellar granule neurons

is a small-molecule inhibitor of the Wnt pathway which is being investigated as a potential disease modifying agent for the treatment of osteoarthritis of the knee

) and by the local perfusion with a low-calcium Ringer solution (Ca2+ 0

WYE-687 IR-124 orally bioavailable inhibitor of classWYE 687 is a potent and ATP competitive and selective inhibitor of mTOR with IC50 of 7 nM. Product information CAS Number: 1062161 90 3 Molecular Weight: 528. 61 Formula: C28H32N8O3 Chemical Name: methyl (4 (4 morpholino 1 (1 (pyridin 3 ylmethyl)piperidin 4 yl) 1H pyrazolo[3, 4 d]pyrimidin 6 yl)phenyl)carbamate Smiles: COC(=O)NC1=CC=C(C=C1)C1=NC(=C2C=NN(C3CCN(CC3)CC3=CC=CN=C3)C2=N1)N1CCOCC1 InChiKey: VDOCQQKGPJENHJ UHFFFAOYSA N InChi: InChI=1S