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5 μM in HeLa cells following treatment over a 24-hour period
3H-SM-3997 bound rapidly
Kanazawa H
Smiles: CC(C)(SC1=CC=C(CCN(CCCCC2CCCCC2)C(=O)NC2CCCCC2)C=C1)C(O)=O
4-c]pyridin-3-one
SNDX-5613 - CAS# 2169919-21-3 midone 5 μM in HeLa cellsSNDX 5613 is a potent and selective inhibitor of menin MLL binding with a Ki of 0. 15 nM. SNDX 5613 shows anti proliferative activity against multiple cell lines harboring MLLr translocations (MV4; 11, RS4; 11, MOLM 13, KOPN 8) with IC50 values ranging from 10 20 nM. Product information CAS Number: 2169919 21 3 Molecular Weight: 630. 82 Formula: C32H47FN6O4S Chemical Name: N ethyl 2 [4 [7 [[4 (ethylsulfonylamino)cyclohexyl]methyl] 2, 7 diazaspiro[3.
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