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O-1602 Catalog No.:M22717-C InChiKey: CKUFOBCNTCLXJP-UHFFFAOYSA-N

SKU: 12815644435

4.1
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Description

InChiKey: CKUFOBCNTCLXJP-UHFFFAOYSA-N

5-dioxo-1-((6-(5-((3aS

6R)-5-amino-4

InChiKey: UFKLYTOEMRFKAD-SHTZXODSSA-N

InChi: InChI=1S/C15H9F2N5O3/c16-9-5-8(15(24)25)12(6-10(9)17)19-14(23)11-1-2-13(21-20-11)22-4-3-18-7-22/h1-7H

O-1602 Catalog No.:M22717-C InChiKey: CKUFOBCNTCLXJP-UHFFFAOYSA-NO 1602 is an agonist of GPR55 (EC50 = 13 nM in a GTPS binding assay) and a derivative of the GPR55 agonist abnormal cannabidiol. It is selective for GPR55 over cannabinoid (CB) receptor 1 (CB1) and CB2 (EC50s = >30 M for both in GTPS binding assays). O 1602 (50 M) reduces growth of Mz ChA 1, HuCCT 1, CC LP 1, and SG231 cholangiocarcinoma cells and reduces tumor growth in a Mz ChA 1 mouse xenograft model when administered at a dose of 10 mg kg per day.

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