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CD8+ T cell depletion abrogates the efficacy of CPI-444 treatment as a single agent as well as in combination with anti-PD-L1
62(12):1200-13
Transfer of RABV G genes with signature resistance mutations into a recombinant VSV backbone resulted in the recovery of replication-competent virions with low susceptibility to the inhibitor
Chemical Name: 1-(4-chlorophenyl)-N-(3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl)-5-methyl-1H-pyrazole-4-carboxamide
Cancer Res 2017
BML-284 HCl - CAS# 2095432-75-8 60286 CD8+ T cell depletion abrogatesBML 284 HCl, CAS No. 2095432 75 8, also known as AMBMP and Wnt agonist 1, is a potent and selective activator of Wnt signaling. It enhances beta catenin and increases transcript and protein levels of p gp. Product information CAS Number: 2095432 75 8 Molecular Weight: 386. 83 Formula: C19H19ClN4O3 Synonym: BML284 HCl AMBMP HCl Wnt Agonist Chemical Name: 4 N (1,3 Benzodioxol 5 ylmethyl) 6 (3 methoxyphenyl)pyrimidine 2,4 diamine Hydrochloride Smiles:
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