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EMI1 (1 nM-100μM) strongly inhibits the viability and increase the caspase 3/7 activity of PC9 EGFR ex19del/T790M/C797S triple-mutant cells than noncancerous human bronchial epithelial (HBE) cells
MCL0020 attenuates swim stress-induced anxiogeniclike behavior in light/dark exploration tests in mice
and SUN concentrations and renal caspase 3/7 activity decreased in 5/6Nx mice treated with NS-03-08
Formula: C17H30Br2N2
protects rat myocardium-derived H9C2 cells against apoptosis
Ranolazine-d8 H-PEG4-CH2COOH EMI1 (1 nM-100μM) strongly inhibitsRanolazine d8 (CVT 303 d8) is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 M and 12 M, respectively) without affecting heart rate or blood pressure (BP). Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor. Antianginal agent. Product information CAS Number: 1092804 88 0 Molecular Weight: 435.