SRI-29329 848ihydrolycorine 4-e]isoindole-1

4-e]isoindole-1

is a functionalized cereblon ligand for PROTAC® research and development

6-dihydroxy-4-methoxycyclohexa-2

and is usually synthesized fromaromatic hydrocarbons

cleave a specific extracellular amino-terminal domain of the receptor to reveal a "tethered ligand"

SRI-29329 848ihydrolycorine 4-e]isoindole-1SRI 29329 is a specific CLK inhibitor, with IC50 values of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively. Product information CAS Number: 2086809 58 5 Molecular Weight: 399. 92 Formula: C20H26ClN7 Chemical Name: N2 [(1S,2S) 2 aminocyclohexyl] N6 (3 chlorophenyl) 9 (propan 2 yl) 9H purine 2,6 diamine Smiles: CC(C)N1C=NC2=C(NC3=CC=CC(Cl)=C3)N=C(N[C@H]3CCCC[C@@H]3N)N=C12 InChiKey: JPJBCKSRGYPABG HOTGVXAUSA N InChi: InChI=1S C20H26ClN7 c1