ARD-266 12896 Smiles: CN(C)CC(=O)NC1C=C2C3=CC=CC=C3C(=O)NC2=CC=1

Smiles: CN(C)CC(=O)NC1C=C2C3=CC=CC=C3C(=O)NC2=CC=1

Vardenafil hydrochloride trihydrate

cell proliferation and differentiation

Formula: C9H13N3O3

InChi: InChI=1S/C9H4Br4O2/c10-5-3-4(1-2-6(14)15)7(11)9(13)8(5)12/h1-3H

ARD-266 12896 Smiles: CN(C)CC(=O)NC1C=C2C3=CC=CC=C3C(=O)NC2=CC=1ARD 266 is a highly potent and VHL E3 ligase based androgen receptor (AR) PROTAC degrader. ARD 266 effectively induces degradation of AR protein in AR positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC50 values of 0. 2 1 nM. Product information Molecular Weight: 915. 51 Formula: C52H59ClN6O7 Chemical Name: (2S,4R) 4 hydroxy 1 [(2R) 3 methyl 2 (3 methyl 1,2 oxazol 5 yl)butanoyl] N [(1S) 3 oxo 1 phenyl 3 {4 [2 (4 {[(1r,3r) 3 (3 chloro 4