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SAR407899 (3 μM) completely blocks thrombin-induced shrinkage of human umbilical vein endothelial cells (HUVECs) and stress fiber formation
TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis
3-benzoxadiazol-7-amine
but not activity of other SCF complexes
Garcia-Pelaez I
VU-0357121 - CAS# 433967-28-3 size:10mg solid SAR407899 (3 μM) completely blocksVU 0357121, CAS No. 433967 28 3, is a positive allosteric modulator of mGlu5 receptors (EC50 = 33 nM). Mutagenesis studies indicate that VU 0357121 and related analogues bind to a yet uncharacterized allosteric site on mGlu(5), distinct from CPPHA, yet share a functional interaction with the MPEP site. Product information CAS Number: 433967 28 3 Molecular Weight: 305. 32 Formula: C17H17F2NO2 Synonym: VU 0357121 VU 0357121 VU0357121 Chemical Name: 4
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