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CP-724714 - CAS# 383432-38-0 Catalog No.:M10878-10 Nutlin-3a induces apoptosis in ~60%

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Description

Nutlin-3a induces apoptosis in ~60% of SJSA-1 and MHMcells after 40 h

GW806742X (0

also known as ABT-888

Chemical Name: 5-{3-[(2-carboxy-4-oxo-4H-chromen-5-yl)oxy]-2-hydroxypropoxy}-4-oxo-4H-chromene-2-carboxylic acid sodium

11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthrene-1

CP-724714 - CAS# 383432-38-0 Catalog No.:M10878-10 Nutlin-3a induces apoptosis in ~60%CP 724714 is An orally bioavailable quinazoline with potential antineoplastic activity. CP 724,714 selectively binds to the intracellular domain of HER2, reversibly inhibiting its tyrosine kinase activity and resulting in suppression of tumor cell growth. HER2, a member of the epidermal growth factor receptor (EGFR) family, is overexpressed in many adenocarcinomas, particularly breast cancers. Product information CAS Number: 383432 38 0 Molecular

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