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SAR407899 is equipotent against human and rat-derived Rho-kinase 2 with inhibition constant values of 36 nM and 41 nM
and in melanoma
4-thiadiazol-2-yl)sulfanyl]quinazoline
pii: S1470-2045(14)71135-0
6R)-6-(aminomethyl)-3
Dasatinib Hydrochloride eamine SAR407899 is equipotent against humanDasatinib hydrochloride (BMS 354825) is the hydrochloride salt form of dasatinib, an inhibitor that targets Abl, Src and c Kit, with IC50 of Product information CAS Number: 854001 07 3 Molecular Weight: 524. 47 Formula: C22H27Cl2N7O2S Chemical Name: N (2 chloro 6 methylphenyl) 2 ({6 [4 (2 hydroxyethyl)piperazin 1 yl] 2 methylpyrimidin 4 yl}amino) 1,3 thiazole 5 carboxamide hydrochloride Smiles: Cl.
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